Advertising revenue supports our not-for-profit mission. What Makes Us Itch? Ibler KS, et al. When it reaches the lungs, it triggers the hypersensitivity characteristic of asthma. What were the results of the study? Most importantly, methods to sample and quantitate skin exposures generally are not well developed or widely available, unlike airborne exposure methods.
Numerous occupational and environmental exposures that increase asthma risk have been identified. Research and prevention have focused primarily on the respiratory tract. However, recent studies suggest that the skin may also be an important route of exposure and site of sensitization that contributes to asthma development. Factors that impair skin barrier function, such as filaggrin gene mutations or skin trauma, may facilitate allergen entry and promote Th2-like sensitization and subsequent asthma. Animal studies demonstrate that skin exposure to chemical and protein allergens is highly effective at inducing sensitization, with subsequent inhalation challenge eliciting asthmatic responses. A similar role for human skin exposure to certain sensitizing agents, such as isocyanates, is likely. Skin exposure methodologies are being developed to incorporate skin exposure assessment into epidemiology studies investigating asthma risk factors.
Led by doctoral student Shadmehr Shawn Demehri, the researchers studied mice that had been engineered with a genetic defect in patches of whay skin. Atopic Dermatitis Eczema Symptoms Skin, red or dry skin. In press. Testing is also recommended when the child has a history of reaction after eating a specific food. Sjin are small, easy to use, and children who are old enough can learn how to what themselves the injection. However, it can be impossible the your asthma to completely avoid certain allergens. Occup What is arthritis lower back Med ; 63 —